Applications | Castor Optics Inc.

EXAMPLES OF APPLICATIONS

Our couplers are used for applications ranging from surface plasmon resonance (SPR) sensing to optical coherence tomography (OCT) imaging. With partners from around the globe, Castor's couplers have been used in biology and medical applications. Below, you will find links to these articles. You find these results inspiring? Drop us a line and we will see how we can help you integrate our couplers into your setup. Enjoy reading!

Review paper Castor Optics' team wrote a review paper on advances in multimodal imaging using DCFCs. This paper reviews the operation and types of DCFCs in addition to current biomedical applications.	Combined immuno-NIRF and OCT Feroldi et al. show a new application for Castor's DCFC, combined near-infrared immunofluorescence and optical coherence tomography to image tumor in situ in a xenograft mouse model. Results using a handheld scanner and an endoscope are shown. The authors further characterized generation of photoluminescence within a DCF.
Combined imaging and sensing probe Li et al. present the use of a Castor's module to combine OCT imaging and temperature sensing capabilities within a single-fiber needle probe. This module comprises of a wavelength division multiplexer and a DCFC.	Confocal displacement sensor Castor's DCFC is used as part of a single fiber dual-detection confocal displacement sensor. The DCF's core and inner cladding relay the light to each detector as shown by Lee et al.
Handheld confocal microencoscope Professor Maitland and her team at Texas A&M University used Castor's DCFC for in vivo imaging of oral epithelium using a handheld confocal microendoscope.	In vivo OCT endoscopy Castor's couplers used by BC Cancer Agency to provide combined OCT/fluorescence endoscopic data of the human lung in vivo.
Ophthalmic OCT and SLO In Prof. Tao's laboratory, Castor's couplers were used to provide simultaneous ophthalmic imaging using laser scanning ophthalmoscopy and OCT.	Color imaging over OCT Stanford University and Polytechnique Montreal teamed up to demonstrate hyperspectral imaging coupled to OCT in a JBO publication authored by Guay-Lord et al.
OCT & fluorescence imaging Scolaro & al showed that combining Castor's DCFC with a needle probe, combined OCT (gray scale) & fluorescence (green) imaging could be performed deep within tissues. This provides structural (OCT) as well as molecular (fluorescence) imaging.	Laser coagulation monitored with OCT Harvard Medical School and Polytechnique Montréal teamed up to demonstrate concurrent OCT imaging and laser coagulation through a novel double-clad fiber design. A publication authored by Beaudette et al.
Speckle-free 3D imaging Through Lemire-Renaud et al's paper, we were the first to shows efficient multimode transfer in a DCFC. This was used, in this paper, to obtain speckle-free images (from the multimode inner cladding) coupled to 3D interferometric imaging (from the core).	Etendue Castor's secret sauce: multi-mode transfer as a function of the ratio of etendues, G, of both fibers. The etendue, for fiber optics, is given by the product of the cross section, A, and the square of the numerical aperture, NA, as explained in this paper from Madore et al.
Tilted Bragg Grating In Diaa Baiad et al's paper, a DCFC is used to capture the reflected cladding modes from a fiber Bragg grating sensor measuring the surrounding refractive index.	DCFC_SPR Castor's DCFC used in this publication for efficient surface plasmon resonance (SPR) sensing theough the collection of cladding modes by Diaa Baiad et al.

EXAMPLES OF APPLICATIONS

Review paper

Castor Optics' team wrote a review paper on advances in multimodal imaging using DCFCs. This paper reviews the operation and types of DCFCs in addition to current biomedical applications.

Combined immuno-NIRF and OCT

Combined imaging and sensing probe

Li et al. present the use of a Castor's module to combine OCT imaging and temperature sensing capabilities within a single-fiber needle probe. This module comprises of a wavelength division multiplexer and a DCFC.

Confocal displacement sensor

Castor's DCFC is used as part of a single fiber dual-detection confocal displacement sensor. The DCF's core and inner cladding relay the light to each detector as shown by Lee et al.

Handheld confocal microencoscope

Professor Maitland and her team at Texas A&M University used Castor's DCFC for in vivo imaging of oral epithelium using a handheld confocal microendoscope.

In vivo OCT endoscopy

Castor's couplers used by BC Cancer Agency to provide combined OCT/fluorescence endoscopic data of the human lung in vivo.

Ophthalmic OCT and SLO

In Prof. Tao's laboratory, Castor's couplers were used to provide simultaneous ophthalmic imaging using laser scanning ophthalmoscopy and OCT.

Color imaging over OCT

Stanford University and Polytechnique Montreal teamed up to demonstrate hyperspectral imaging coupled to OCT in a JBO publication authored by Guay-Lord et al.

OCT & fluorescence imaging

Scolaro & al showed that combining Castor's DCFC with a needle probe, combined OCT (gray scale) & fluorescence (green) imaging could be performed deep within tissues. This provides structural (OCT) as well as molecular (fluorescence) imaging.

Laser coagulation monitored with OCT

Harvard Medical School and Polytechnique Montréal teamed up to demonstrate concurrent OCT imaging and laser coagulation through a novel double-clad fiber design. A publication authored by Beaudette et al.

Speckle-free 3D imaging

Through Lemire-Renaud et al's paper, we were the first to shows efficient multimode transfer in a DCFC. This was used, in this paper, to obtain speckle-free images (from the multimode inner cladding) coupled to 3D interferometric imaging (from the core).

Etendue

Castor's secret sauce: multi-mode transfer as a function of the ratio of etendues, G, of both fibers. The etendue, for fiber optics, is given by the product of the cross section, A, and the square of the numerical aperture, NA, as explained in this paper from Madore et al.

Tilted Bragg Grating

In Diaa Baiad et al's paper, a DCFC is used to capture the reflected cladding modes from a fiber Bragg grating sensor measuring the surrounding refractive index.

DCFC_SPR

Castor's DCFC used in this publication for efficient surface plasmon resonance (SPR) sensing theough the collection of cladding modes by Diaa Baiad et al.